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LRIG1 gene copy number analysis by ddPCR and correlations to clinical factors in breast cancer

Abstract Background Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) copy number alterations and unbalanced gene recombination events have been reported to occur in breast cancer. Importantly, LRIG1 loss was recently shown to predict early and late relapse in stage I-II breast cancer....

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Principais autores: Mahmood Faraz, Andreas Tellström, Christina Edwinsdotter Ardnor, Kjell Grankvist, Lukasz Huminiecki, Björn Tavelin, Roger Henriksson, Håkan Hedman, Ingrid Ljuslinder
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-05-01
Serier:BMC Cancer
Fag:
Breast cancer
LRIG1
Gene copy number
ddPCR
Prognosis
Online adgang:http://link.springer.com/article/10.1186/s12885-020-06919-w
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