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SARS-CoV-2 neutralizing antibody specificities differ dramatically between recently infected infants and immune-imprinted individuals

ABSTRACT The immune response to viral infection is shaped by past exposures to related virus strains, a phenomenon known as imprinting. For severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), much of the population has been imprinted by a viral spike from an early strain, either through va...

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Principais autores: Bernadeta Dadonaite, Allison R. Burrell, Jenni Logue, Helen Y. Chu, Daniel C. Payne, David B. Haslam, Mary A. Staat, Jesse D. Bloom
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2025-04-01
coleção:Journal of Virology
Assuntos:
SARS-CoV-2
immunology
virology
evolution
antibody repertoire
antigenic variation
Acesso em linha:https://journals.asm.org/doi/10.1128/jvi.00109-25
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