Influence of Rheumatoid Factors on the Efficacy of TNF Inhibitor Therapy in Patients with Rheumatoid Arthritis

Abstract Introduction Although the efficacy of tumor necrosis factor inhibitors (TNFi) is reduced in patients with rheumatoid factor (RF)-high rheumatoid arthritis (RA), certolizumab pegol (CZP), lacking the Fc portion, may not be affected. This study aimed to compare CZP with Fc-containing TNFi and...

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Autori principali:	Atsushi Nagayasu, Yusuke Miyazaki, Koshiro Sonomoto, Satoshi Kubo, Ippei Miyagawa, Ayako Yamaguchi, Hiroaki Tanaka, Yasuyuki Todoroki, Masanobu Ueno, Takafumi Aritomi, Yuya Fujita, Hidenori Sakai, Katsunori Suzuki, Shingo Nakayamada, Yoshiya Tanaka
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Adis, Springer Healthcare 2025-05-01
Serie:	Rheumatology and Therapy
Soggetti:	Certolizumab pegol Rheumatoid arthritis Rheumatoid factor Tumor necrosis factor inhibitor
Accesso online:	https://doi.org/10.1007/s40744-025-00769-3
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