Pathogenesis of chronic rhinosinusitis with nasal polyps: role of IL-6 in airway epithelial cell dysfunction

Abstract Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by an alteration in airway epithelial cell functions including barrier function, wound repair mechanisms, mucociliary clearance. The mechanisms leading to epithelial cell dysfunction in nasal polyps (NPs) remain p...

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Hlavní autoři:	Emilie Bequignon, David Mangin, Justine Bécaud, Jennifer Pasquier, Christelle Angely, Mathieu Bottier, Estelle Escudier, Daniel Isabey, Marcel Filoche, Bruno Louis, Jean-François Papon, André Coste
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2020-03-01
Edice:	Journal of Translational Medicine
Témata:	Nasal Polyps IL-6 Interleukin 6 Inflammation Repair mechanisms Mucociliary clearance
On-line přístup:	http://link.springer.com/article/10.1186/s12967-020-02309-9
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