Decoding pilocarpine biosynthesis and its roles in Pilocarpus microphyllus through a comparative transcriptomics approach

Abstract Background Pilocarpus microphyllus, widely known as jaborandi, faces a decline in its natural population due to unsustainable harvesting for pilocarpine extraction, an imidazole alkaloid with significant pharmacological properties. This study presents the first comparative transcriptomic an...

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Main Authors:	Mariane Brom Sobreiro, Giordano Bruno Soares-Souza, Leandro Magalhães, Débora de Morais Cordeiro, Michele Molina, Santelmo Vasconcelos, Yan Nunes Dias, Renato R. Moreira-Oliveira, Markus Gastauer, Silvio Ramos, Guilherme Oliveira, Cecílio Frois Caldeira, Amanda F. Vidal
Format:	Artigo
Language:	Inglês
Published:	BMC 2025-08-01
Series:	BMC Plant Biology
Subjects:	RNA-Seq Jaborandi Pilocarpine Conservation
Online Access:	https://doi.org/10.1186/s12870-025-07087-4
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