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NOTCH signaling in COVID-19: a central hub controlling genes, proteins, and cells that mediate SARS-CoV-2 entry, the inflammatory response, and lung regeneration

In the lungs of infected individuals, the downstream molecular signaling pathways induced by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) are incompletely understood. Here, we describe and examine predictions of a model in which NOTCH may represent a central signaling axis in lung in...

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Principais autores: Piyush Baindara, Md Bodruzzaman Sarker, Alexander P. Earhart, Santi M. Mandal, Adam G. Schrum
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2022-08-01
סדרה:Frontiers in Cellular and Infection Microbiology
נושאים:
ADAM
ACE2
furin
Notch
SARS-CoV-2
COVID-19
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fcimb.2022.928704/full
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