Genome-Wide Mapping Defines a Role for C/EBPβ and c-Jun in Non-Canonical Cyclic AMP Signalling

The novel exchange protein activated by cyclic AMP (EPAC1) activator, I942, induces expression of the suppressor of cytokine signalling 3 (SOCS3) gene, thereby inhibiting interleukin 6 (IL6) inflammatory processes in human umbilical vein endothelial cells (HUVECs). Here we use RNA-SEQ and ChIP-SEQ t...

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Auteurs principaux:	Jolanta Wiejak, Boy van Basten, Graham Hamilton, Stephen J. Yarwood
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2019-10-01
Collection:	Cells
Sujets:	vascular endothelial cells cyclic amp epac1 c-jun c/ebpβ transcriptome chromatin cell adhesion molecules
Accès en ligne:	https://www.mdpi.com/2073-4409/8/10/1253
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