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GLI1+ perivascular, renal, progenitor cells: The likely source of spontaneous neoplasia that created the AGMK1-9T7 cell line.

The AGMK1-9T7 cell line has been used to study neoplasia in tissue culture. By passage in cell culture, these cells evolved to become tumorigenic and metastatic in immunodeficient mice at passage 40. Of the 20 x 106 kidney cells originally plated, less than 2% formed the colonies that evolved to cre...

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Autores principales: Andrew M Lewis, Gideon Foseh, Wei Tu, Keith Peden, Adovi Akue, Mark KuKuruga, Daniel Rotroff, Gladys Lewis, Ilya Mazo, Steven R Bauer
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2023-01-01
Colección:PLoS ONE
Acceso en línea:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0293406&type=printable
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