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Small interfering RNAs targeting agrA and sarA attenuate pathogenesis of Staphylococcus aureus in Caenorhabditis elegans

Introduction: The use of small interfering RNA (siRNA) gene silencing is a promising therapeutic option as it does not impose selective pressure on bacteria that is often associated with the development of resistance. The study assessed the effect of siRNA targeted to sarA and agrA in S. aureus and...

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Autori principali: Terissa Alexas Thompson, Paul Dean Brown
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Journal of Infection in Developing Countries 2021-12-01
Serie:Journal of Infection in Developing Countries
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Accesso online:https://jidc.org/index.php/journal/article/view/13664
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