A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
Summary: Mouse embryonic stem cells (mESCs) in the primed pluripotency state, which resembles the post-implantation epiblast, can be de-differentiated in culture to a naive state that resembles the pre-implantation inner cell mass. We report that primed-to-naive mESC transition entails a significant...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2024-04-01
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| Serija: | Cell Reports |
| Teme: | |
| Online pristup: | http://www.sciencedirect.com/science/article/pii/S2211124724003528 |
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