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Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro.

Microtubule structure and functions have been widely studied in vitro and in cells. Research has shown that cysteines on tubulin play a crucial role in the polymerization of microtubules. Here, we show that blocking sulfhydryl groups of cysteines in taxol-stabilized polymerized microtubules with a c...

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Autors principals: Meenakshi Prabhune, Kerstin von Roden, Florian Rehfeldt, Christoph F Schmidt
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2016-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4999061?pdf=render
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