Caffeic Acid Acts as a Potent Senomorphic and Alleviates Inflammation and Lung Fibrosis by Covalently Targeting Annexin A5 Protein in Mice

ABSTRACT The accumulation of senescent cells and their secretion of senescence‐associated secretory phenotype (SASP) play important roles in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Small molecules, known as senolytics or senomorphics, have been effective in targeting senescent cells...

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Detalhes bibliográficos

Principais autores:	Yinhua Zhu, Ying Zhang, Qianyu Zhang, Ping Song, Junzhe Zhang, Ang Ma, Chen Wang, Peng Gao, Tong Yang, Lirun Zhou, Qiaoli Shi, Yin Kwan Wong, Yongting Luo, Huan Tang, Jigang Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-12-01
coleção:	Exploration
Assuntos:	annexin A5 caffeic acid SASP senescent cells senomorphics
Acesso em linha:	https://doi.org/10.1002/EXP.20240069
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