Depletion of PCAT-1 in head and neck cancer cells inhibits tumor growth and induces apoptosis by modulating c-Myc-AKT1-p38 MAPK signalling pathways

Abstract Background Head and neck squamous cell carcinoma (HNSCC) represents one of the most common malignancies worldwide with a high mortality rate mainly due to lack of early detection markers, frequent association with metastasis and aggressive phenotype. Recently, long non-coding RNAs (lncRNAs)...

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Hauptverfasser:	Subhayan Sur, Hiroshi Nakanishi, Robert Steele, Ratna B. Ray
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2019-04-01
Schriftenreihe:	BMC Cancer
Schlagworte:	Head and neck squamous cell carcinoma (HNSCC) Long non-coding RNA PCAT-1 c-Myc-AKT1signaling Tumorigenicity
Online-Zugang:	http://link.springer.com/article/10.1186/s12885-019-5562-z
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