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An evaluation of the genome-wide false positive rates of common methods for identifying differentially methylated regions using illumina methylation arrays

Differentially methylated regions (DMRs) are genomic regions with specific methylation patterns across multiple loci that are associated with a phenotype. We examined the genome-wide false positive (GFP) rates of five widely used DMR methods: comb-p, Bumphunter, DMRcate, mCSEA and coMethDMR using bo...

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Bibliografiske detaljer
Principais autores: Yuanchao Zheng, Kathryn L. Lunetta, Chunyu Liu, Seyma Katrinli, Alicia K. Smith, Mark W. Miller, Mark W. Logue
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2022-12-01
Serier:Epigenetics
Fag:
Online adgang:http://dx.doi.org/10.1080/15592294.2022.2115600
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