Characterization of Chicken IgY Specific to Clostridium difficile R20291 Spores and the Effect of Oral Administration in Mouse Models of Initiation and Recurrent Disease

Clostridium difficile infection (CDI) are the leading cause of world-wide nosocomial acquired diarrhea. The current main clinical challenge in CDI is the elevated rate of infection recurrence that may reach up to 30% of the patients, which has been associated to the formation of dormant spores durin...

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Główni autorzy:	Marjorie Pizarro-Guajardo, Fernando Díaz-González, Manuel Álvarez-Lobos, Daniel Paredes-Sabja
Format:	Artigo
Język:	Inglês
Wydane:	Frontiers Media S.A. 2017-08-01
Seria:	Frontiers in Cellular and Infection Microbiology
Hasła przedmiotowe:	Clostridium difficile spores chicken immunoglobulin IgY immunotherapy passive immunization recurrent CDI exosporium
Dostęp online:	http://journal.frontiersin.org/article/10.3389/fcimb.2017.00365/full
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