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Ageing-Induced Decline in Primary Myeloid Cell Phagocytosis Is Unaffected by Optineurin Insufficiency

Optineurin is a ubiquitin-binding adaptor protein involved in multiple cellular processes, including innate inflammatory signalling. Mutations in optineurin were found in amyotrophic lateral sclerosis, an adult-onset fatal neurodegenerative disease that targets motor neurons. Neurodegeneration resul...

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Bibliografiske detaljer
Principais autores: Josip Peradinovic, Nikolina Mohovic, Katarina Bulic, Andrea Markovinovic, Raffaello Cimbro, Ivana Munitic
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-02-01
Serier:Biology
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Online adgang:https://www.mdpi.com/2079-7737/12/2/240
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