Ageing-Induced Decline in Primary Myeloid Cell Phagocytosis Is Unaffected by Optineurin Insufficiency
Optineurin is a ubiquitin-binding adaptor protein involved in multiple cellular processes, including innate inflammatory signalling. Mutations in optineurin were found in amyotrophic lateral sclerosis, an adult-onset fatal neurodegenerative disease that targets motor neurons. Neurodegeneration resul...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
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MDPI AG
2023-02-01
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| Serier: | Biology |
| Fag: | |
| Online adgang: | https://www.mdpi.com/2079-7737/12/2/240 |
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