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Genetic Variation in <i>CYP2D6</i> and <i>SLC22A1</i> Affects Amlodipine Pharmacokinetics and Safety

Amlodipine is an antihypertensive drug with unknown pharmacogenetic biomarkers. This research is a candidate gene study that looked for associations between amlodipine pharmacokinetics and safety and pharmacogenes. Pharmacokinetic and safety data were taken from 160 volunteers from eight bioequivale...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Paula Soria-Chacartegui, Pablo Zubiaur, Dolores Ochoa, Gonzalo Villapalos-García, Manuel Román, Miriam Matas, Laura Figueiredo-Tor, Gina Mejía-Abril, Sofía Calleja, Alejandro de Miguel, Marcos Navares-Gómez, Samuel Martín-Vilchez, Francisco Abad-Santos
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-01-01
Schriftenreihe:Pharmaceutics
Schlagworte:
pharmacogenetics
amlodipine
CYP2D6
SLC22A1
Online-Zugang:https://www.mdpi.com/1999-4923/15/2/404
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