Resolvin D5 Inhibits Neuropathic and Inflammatory Pain in Male But Not Female Mice: Distinct Actions of D-Series Resolvins in Chemotherapy-Induced Peripheral Neuropathy

Earlier studies have demonstrated that essential fatty acid-derived specialized pro-resolving mediators (SPMs) promote the resolution of inflammation and pain. However, the potential analgesic actions of SPMs in chemotherapy-induced peripheral neuropathy (CIPN) are not known. Recent results also sho...

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Principais autores:	Xin Luo, Yun Gu, Xueshu Tao, Charles Nicholas Serhan, Ru-Rong Ji
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-07-01
coleção:	Frontiers in Pharmacology
Assuntos:	chemotherapy-induced peripheral neuropathy (CIPN) docosahexaenoic acid (DHA) intrathecal injection neuropathic pain resolvin D-series (RvDs) sex dimorphism
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2019.00745/full
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