Insights into the modulation of dopamine transporter function by amphetamine, orphenadrine and cocaine binding

Human dopamine transporter (hDAT) regulates dopaminergic signaling in the central nervous system by maintaining the synaptic concentration of dopamine (DA) at physiological levels, upon reuptake of DA into presynaptic terminals. DA translocation involves the co-transport of two sodium ions and the c...

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Detalhes bibliográficos

Principais autores:	Mary Hongying Cheng, Ethan eBlock, Feizhuo eHu, Murat Can Cobanoglu, Alexander eSorkin, Ivet eBahar
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2015-06-01
coleção:	Frontiers in Neurology
Assuntos:	Amphetamine Cocaine Dopamine Orphenadrine human dopamine transporter repurposable drugs
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00134/full
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