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SCM-198 ameliorates the quality of postovulatory and maternally aged oocytes by reducing oxidative stress

Abstract Oocyte aging is a key constraint on oocyte quality, leading to fertilization failure and abnormal embryonic development. In addition, it is likely to generate unfavorable assisted reproductive technology (ART) outcomes. SCM-198, a synthetic form of leonurine, was found to rescue the rate of...

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Principais autores: Wei Ma, Xi Zhao, Qingxin Wang, Xue Wu, Tingting Yang, Yuqi Chen, Yizhun Zhu, Xia Wang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-08-01
coleção:Journal of Ovarian Research
Assuntos:
Apoptosis
Oxidative stress
Oocyte quality
Postovulatory aging
SCM-198
Acesso em linha:https://doi.org/10.1186/s13048-024-01504-2
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