Multivalent viral particles elicit safe and efficient immunoprotection against Nipah Hendra and Ebola viruses

Abstract Experimental vaccines for the deadly zoonotic Nipah (NiV), Hendra (HeV), and Ebola (EBOV) viruses have focused on targeting individual viruses, although their geographical and bat reservoir host overlaps warrant creation of multivalent vaccines. Here we explored whether replication-incompet...

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Detalhes bibliográficos

Principais autores:	Duncan G. Ithinji, David W. Buchholz, Shahrzad Ezzatpour, I. Abrrey Monreal, Yu Cong, Julie Sahler, Amandip Singh Bangar, Brian Imbiakha, Viraj Upadhye, Janie Liang, Andrew Ma, Birgit Bradel-Tretheway, Benjamin Kaza, Yao Yu Yeo, Eun Jin Choi, Gunner P. Johnston, Louis Huzella, Erin Kollins, Saurabh Dixit, Shuiqing Yu, Elena Postnikova, Victoria Ortega, Avery August, Michael R. Holbrook, Hector C. Aguilar
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2022-12-01
Colecção:	npj Vaccines
Acesso em linha:	https://doi.org/10.1038/s41541-022-00588-5
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