Increased integration and synergy in EEG- and fNIRS-based data in migraine patients after a three-month treatment with galcanezumab: relations with long-term clinical outcome

Abstract Galcanezumab is a well-tolerated monoclonal antibody developed for migraine prophylaxis. Although its action mechanisms are not fully understood, they may involve changes in cortical connectivity. This study explores galcanezumab-induced central changes by investigating metabolic-electrical...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Marianna La Rocca, Antonio Lacalamita, Livio Clemente, Giulia Paparella, Elena Ammendola, Nicola Amoroso, Emmanuella Ladisa, Alfonso Monaco, Sebastiano Stramaglia, Roberto Bellotti, Marina de Tommaso
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-12-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Functional near infrared spectroscopy Electroencephalography Brain connectivity High-order interaction Migraine Galcanezumab
Online-Zugang:	https://doi.org/10.1038/s41598-025-30274-0
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