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Targeting USP22 to promote K63-linked ubiquitination and degradation of SARS-CoV-2 nucleocapsid protein

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) generally hijacks the cellular machinery of host cells for survival. However, how SARS-CoV-2 employs the host’s deubiquitinase to facilitate virus replication remains largely unknown. In this study, we identified the host deubiqui...

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Bibliografiske detaljer
Principais autores: Xin Xiao, Shifeng Li, Zhijin Zheng, Yingying Ji, Qian Du, Yibo Zuo, Ying Miao, Yukang Yuan, Hui Zheng, Fang Huang, Jun Wang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2025-05-01
Serier:Journal of Virology
Fag:
Online adgang:https://journals.asm.org/doi/10.1128/jvi.02234-24
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