Heterogeneous distribution pattern of CD3+ tumor-infiltrated lymphocytes (TILs) and high combined positive score (CPS) favored the prognosis of resected early stage small-cell lung cancer

Purpose: This study aimed to illustrate the heterogeneity of immune features in small cell lung cancer (SCLC). Methods: Immunohistochemistry (IHC) staining of CD3, CD4, CD8 and PD-L1 were performed with 55 SCLC FFPE samples from radical resections. Quantitative assessment of CD3+ tumor-infiltrated l...

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Principais autores:	Liang Zhu, Guoping Cheng, Meijuan Wu, Ming Chen, Ying Jin
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2023-08-01
Serija:	Translational Oncology
Teme:	Small-cell lung cancer Heterogeneity Tumor-infiltrated lymphocytes Tumor positive score Combined positive score Survival
Online dostop:	http://www.sciencedirect.com/science/article/pii/S1936523323000839
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