Leveraging Immunofocusing and Virus-like Particle Display to Enhance Antibody Responses to the Malaria Blood-Stage Invasion Complex Antigen PfCyRPA

A vaccine protecting against malaria caused by <i>Plasmodium falciparum</i> is urgently needed. The blood-stage invasion complex PCRCR consists of the five malarial proteins PfPTRAMP, PfCSS, PfRipr, PfCyRPA, and PfRH5. As each subcomponent represents an essential and highly conserved antigen, PCRCR...

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Auteurs principaux:	Kasper H. Björnsson, Maria R. Bassi, Anne S. Knudsen, Kara-Lee Aves, Èlia Morella Roig, Adam F. Sander, Lea Barfod
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2024-07-01
Collection:	Vaccines
Sujets:	malaria blood-stage vaccine development PfCyRPA immunofocusing VLP PCRCR invasion complex
Accès en ligne:	https://www.mdpi.com/2076-393X/12/8/859
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