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Epigenetic identification of mitogen-activated protein kinase 10 as a functional tumor suppressor and clinical significance for hepatocellular carcinoma

Background Mitogen-activated protein kinase 10 (Mapk10) is a member of the c-jun N-terminal kinases (jnk) subgroup in the MAPK superfamily, and was proposed as a tumor suppressor inactivated epigenetically. Its role in hepatocellular carcinoma (HCC) has not yet been illustrated. We aimed to investig...

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Principais autores: Liping Tang, Shasha Zhu, Weiyan Peng, Xuedong Yin, Cui Tan, Yaying Yang
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2021-02-01
coleção:PeerJ
Assuntos:
hepatocellular carcinoma
mapk10
Tumor suppressor gene
Methylation
Acesso em linha:https://peerj.com/articles/10810.pdf
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