Cell fate in colon cancer stem cells: To GLI or not to GLI?*
Colon cancer is a heterogeneous tumor driven by subpopulations of cancer stem cells (CSCs). We recently used patient-derived organoids (PDOs) to demonstrate that CSC survival is regulated by autocrine non-canonical Hedgehog signaling, which acts as a positive regulator of Wnt signaling to block CSC...
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| Главный автор: | |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis Group
2018-05-01
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| Серии: | Molecular & Cellular Oncology |
| Предметы: | |
| Online-ссылка: | http://dx.doi.org/10.1080/23723556.2018.1445940 |
| Метки: |
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