The methyltransferase activity of Dot1L is essential for Xenopus tropicalis tadpole development and survival
Abstract Epigenetic modifications of histones play key roles in transcriptional regulation by diverse transcription factors. One such modification is the methylation of histone H3 at lysine 79 (H3K79). The methyltransferase DOT1L is the only known, highly conserved enzyme capable of methylating H3K7...
محفوظ في:
| المؤلفون الرئيسيون: | , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
BMC
2026-03-01
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| سلاسل: | Cell & Bioscience |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1186/s13578-026-01537-8 |
| الوسوم: |
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