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Formulation development, in vivo bioequivalence and pediatric PBPK modeling studies of taste-masked ciprofloxacin chewable tablets

Abstract A taste-masked chewable tablet of ciprofloxacin using ion exchange resin Kyron T-134 for enhancing compliance for the paediatric population was developed. The drug-to-resin ratio was optimized for maximum taste masking by studying the effects of soaking time (X1) and mixing time (X2) on com...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Muhammad Talha Usmani, Muhammad Harris Shoaib, Fahad Siddiqui, Farrukh Rafiq Ahmed, Rabia Ismail Yousuf, Muhammad Talha Saleem
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2023-09-01
Cyfres:Scientific Reports
Mynediad Ar-lein:https://doi.org/10.1038/s41598-023-43423-0
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