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Nanopore sequencing provides snapshots of the genetic variation within salmonid alphavirus-3 (SAV3) during an ongoing infection in Atlantic salmon (Salmo salar) and brown trout (Salmo trutta)

Abstract Frequent RNA virus mutations raise concerns about evolving virulent variants. The purpose of this study was to investigate genetic variation in salmonid alphavirus-3 (SAV3) over the course of an experimental infection in Atlantic salmon and brown trout. Atlantic salmon and brown trout parr...

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Uloženo v:
Hlavní autoři: HyeongJin Roh, Kai Ove Skaftnesmo, Dhamotharan Kannimuthu, Abdullah Madhun, Sonal Patel, Bjørn Olav Kvamme, H. Craig Morton, Søren Grove
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-09-01
Edice:Veterinary Research
Témata:
Salmonid alphavirus (SAV)
nanopore sequencing
viral mutation
E2 gene
spike protein
viral heterogeneity
On-line přístup:https://doi.org/10.1186/s13567-024-01349-z
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