Hypoxia inducible factor-1alpha expression correlates with inflammatory injury of blood-brain barrier which influences perihaematomal edema after intracerebral hemorrhage

Backround: In patients with intracerebral hemorrhage (ICH), perihematomal edema (PHE) significantly worsens the prognosis. This condition leads to the formation of a hypoxic microenvironment surrounding the blood-brain barrier (BBB), which in turn activates hypoxia-inducible factor-1 alpha (HIF-1α),...

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Κύριοι συγγραφείς:	Jian Wu, Fuli Yan, Yiming Li, Mingang Liang, Yu Guo, Mingfei Yang
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2025-05-01
Σειρά:	Journal of Stroke and Cerebrovascular Diseases
Θέματα:	Hypoxia inducible factor-1 alpha Tumor necrosis factor-α Zonula occludens-1 Perihematomal edema Blood-brain barrier Intracerebral hemorrhage
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S1052305725000485
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