SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer

Summary: Pancreatic ductal adenocarcinoma (PDAC) exhibits distinct molecular subtypes: classical/progenitor and basal-like/squamous. Our study aimed to identify genes contributing to the development of the basal-like/squamous subtype, known for its aggressiveness. Transcriptome analyses revealed con...

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Detalhes bibliográficos

Principais autores:	Yuuki Ohara, Wei Tang, Huaitian Liu, Shouhui Yang, Tiffany H. Dorsey, Helen Cawley, Paloma Moreno, Raj Chari, Mary R. Guest, Azadeh Azizian, Jochen Gaedcke, Michael Ghadimi, Nader Hanna, Stefan Ambs, S. Perwez Hussain
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-12-01
coleção:	Cell Reports
Assuntos:	CP: Cancer CP: Metabolism
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124723014468
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