Targeting Anti-Angiogenic VEGF₁₆₅b–VEGFR1 Signaling Promotes Nitric Oxide Independent Therapeutic Angiogenesis in Preclinical Peripheral Artery Disease Models

Nitric oxide (NO) is the critical regulator of VEGFR2-induced angiogenesis. Neither VEGF-A over-expression nor L-Arginine (NO-precursor) supplementation has been effective in helping patients with Peripheral Artery Disease (PAD) in clinical trials. One incompletely studied reason may be due to the p...

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Egile Nagusiak:	Sivaraman Kuppuswamy, Brian H. Annex, Vijay C. Ganta
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2022-08-01
Saila:	Cells
Gaiak:	angiogenesis anti-angiogenic VEGF-A ischemia growth factor signaling nitric oxide diabetes
Sarrera elektronikoa:	https://www.mdpi.com/2073-4409/11/17/2676
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