Crystal Structure of Human Myotubularin-Related Protein 1 Provides Insight into the Structural Basis of Substrate Specificity.

Myotubularin-related protein 1 (MTMR1) is a phosphatase that belongs to the tyrosine/dual-specificity phosphatase superfamily. MTMR1 has been shown to use phosphatidylinositol 3-monophosphate (PI(3)P) and/or phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) as substrates. Here, we determined the cry...

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Bibliografische Detailangaben

Hauptverfasser:	Seoung Min Bong, Kka-bi Son, Seung-Won Yang, Jae-Won Park, Jea-Won Cho, Kyung-Tae Kim, Hackyoung Kim, Seung Jun Kim, Young Jun Kim, Byung Il Lee
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2016-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	http://europepmc.org/articles/PMC4809516?pdf=render
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