Distinct Transcriptional Programs Control Cross-Priming in Classical and Monocyte-Derived Dendritic Cells

Both classical DCs (cDCs) and monocyte-derived DCs (Mo-DCs) are capable of cross-priming CD8+ T cells in response to cell-associated antigens. We found that Ly-6ChiTREML4− monocytes can differentiate into Zbtb46+ Mo-DCs in response to granulocyte-macrophage colony-stimulating factor (GM-CSF) and int...

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Autori principali:	Carlos G. Briseño, Malay Haldar, Nicole M. Kretzer, Xiaodi Wu, Derek J. Theisen, Wumesh KC, Vivek Durai, Gary E. Grajales-Reyes, Arifumi Iwata, Prachi Bagadia, Theresa L. Murphy, Kenneth M. Murphy
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2016-06-01
Serie:	Cell Reports
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211124716305939
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