Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex

Occludin (OCLN) mutations cause human microcephaly and cortical malformation. A tight junction component thought absent in neuroepithelium after neural tube closure, OCLN isoform-specific expression extends into corticogenesis. Full-length and truncated isoforms localize to neuroprogenitor centrosom...

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Podrobná bibliografie

Hlavní autoři:	Raphael M Bendriem, Shawn Singh, Alice Abdel Aleem, David A Antonetti, M Elizabeth Ross
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2019-12-01
Edice:	eLife
Témata:	centrosome regulation cortical neurogenesis microcephaly OCLN tight junction protein brain malformation
On-line přístup:	https://elifesciences.org/articles/49376
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