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Concurrent Infection With the Filarial Helminth Litomosoides sigmodontis Attenuates or Worsens Influenza A Virus Pathogenesis in a Stage-Dependent Manner

Filarial helminths infect approximately 120 million people worldwide initiating a type 2 immune response in the host. Influenza A viruses stimulate a virulent type 1 pro-inflammatory immune response that in some individuals can cause uncontrolled immunopathology and fatality. Although coinfection wi...

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Principais autores: Gareth R. Hardisty, Johanna A. Knipper, Alison Fulton, John Hopkins, Bernadette M. Dutia, Matthew D. Taylor
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-01-01
coleção:Frontiers in Immunology
Assuntos:
helminth
coinfection
mouse
respiratory virus
filariasis
influenza A virus
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2021.819560/full
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