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Inorganic polyphosphate suppresses lipopolysaccharide-induced inducible nitric oxide synthase (iNOS) expression in macrophages.

In response to infection, macrophages produce a series of inflammatory mediators, including nitric oxide (NO), to eliminate pathogens. The production of these molecules is tightly regulated via various mechanisms, as excessive responses are often detrimental to host tissues. Here, we report that ino...

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Detalhes bibliográficos
Principais autores: Kana Harada, Toshikazu Shiba, Kazuya Doi, Koji Morita, Takayasu Kubo, Yusuke Makihara, Adriano Piattelli, Yasumasa Akagawa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3767636?pdf=render
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