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Luteolin inhibits triple-negative breast cancer by inducing apoptosis and autophagy through SGK1-FOXO3a-BNIP3 signaling

Background: Triple-negative breast cancer (TNBC) is one of the most prominent neoplasm disorders and lacks efficacious treatments yet. Luteolin (3′,4′,5,7-tetrahydroxyflavone), a natural flavonoid commonly presented in plants, has been reported to delay the progression of TNBC. However, the precise...

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Principais autores: Ling Wu, Yingda Lin, Songyu Gao, Yongfang Wang, Huiji Pan, Zhaozhi Wang, Marina Pozzolini, Fengling Yang, Haiyan Zhang, Yi Yang, Liang Xiao, Yuan Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-06-01
coleção:Frontiers in Pharmacology
Assuntos:
triple-negative breast cancer
luteolin
SGK1
BNIP3
apoptosis
autophagy
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2023.1200843/full
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