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Differences in neutralizing antibody sensitivities and envelope characteristics indicate distinct antigenic properties of Nigerian HIV-1 subtype G and CRF02_AG

Abstract The magnitude of the HIV-1 epidemic in Nigeria is second only to the subtype C epidemic in South Africa, yet the subtypes prevalent in Nigeria require further characterization. A panel of 50 subtype G and 18 CRF02_AG Nigerian HIV-1 pseudoviruses (PSV) was developed and envelope coreceptor u...

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Autori principali: Lindsay Wieczorek, David Chang, Eric Sanders-Buell, Michelle Zemil, Elizabeth Martinez, Jesse Schoen, Agnes-Laurence Chenine, Sebastian Molnar, Brittani Barrows, Kultida Poltavee, Man E. Charurat, Alash’le Abimiku, William Blattner, Michael Iroezindu, Afoke Kokogho, Nelson L. Michael, Trevor A. Crowell, Julie A. Ake, Sodsai Tovanabutra, Victoria R. Polonis, on behalf of the AFRICOS and TRUST/RV368 Study Groups
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2024-06-01
Serie:Virology Journal
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Accesso online:https://doi.org/10.1186/s12985-024-02394-y
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