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Assay establishment and validation of a high-throughput organoid-based drug screening platform

Abstract Background Organoids are three-dimensional structures that closely recapitulate tissue architecture and cellular composition, thereby holding great promise for organoid-based drug screening. Although growing in three-dimensional provides the possibility for organoids to recapitulate main fe...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Xiaomeng Li, Guoxiang Fu, Long Zhang, Ruoyu Guan, Peiyuan Tang, Jialing Zhang, Xinxin Rao, Shengzhi Chen, Xiaoya Xu, Yi Zhou, Yun Deng, Tao Lv, Xingfeng He, Shaobo Mo, Peiyuan Mu, Jianjun Gao, Guoqiang Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-05-01
Schriftenreihe:Stem Cell Research & Therapy
Schlagworte:
Organoid
Z-stack
Fluorescence
High-throughput
Drug screening
Online-Zugang:https://doi.org/10.1186/s13287-022-02902-3
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