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Insulin-Like Growth Factor 1 Attenuates the Pro-Inflammatory Phenotype of Neutrophils in Myocardial Infarction

Acute myocardial infarction (MI) induces an extensive sterile inflammation, which is dominated in the early phase by invading neutrophils and monocytes/macrophages. The inflammatory response after MI critically affects infarct healing and cardiac remodeling. Therefore, modulation of cardiac inflamma...

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Principais autores: Rianne Nederlof, Sophia Reidel, André Spychala, Stefanie Gödecke, André Heinen, Tobias Lautwein, Patrick Petzsch, Karl Köhrer, Axel Gödecke
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-07-01
coleção:Frontiers in Immunology
Assuntos:
insulin-like growth factor 1
myocardial infarction
neutrophil
signaling
inflammation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.908023/full
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