Combining mass spectrometry and machine learning models for predicting Klebsiella pneumoniae antimicrobial resistance: a multicenter experience from clinical isolates in Italy

Abstract Background Multidrug-resistant Klebsiella pneumoniae represents a significant challenge in healthcare settings, prompting numerous studies on the rapid detection of antimicrobial resistance. Mass spectrometry has been recently integrated into routine laboratory diagnostics, providing highly...

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Principais autores:	Ettore Rocchi, Emanuele Nicitra, Maddalena Calvo, Valeria Cento, Laura Peiretti, Zian Asif, Giulia Menchinelli, Brunella Posteraro, Claudia Sala, Claudia Colosimo, Monica Cricca, Vittorio Sambri, Maurizio Sanguinetti, Gastone Castellani, Stefania Stefani
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-01-01
Series:	BMC Microbiology
Assuntos:	Klebsiella pneumoniae Antimicrobial resistance Amikacin Meropenem Mass spectrometry MALDI-TOF
Acceso en liña:	https://doi.org/10.1186/s12866-025-04657-2
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