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Integrin-specific signaling drives ER stress-dependent atherogenic endothelial activation

Atherogenic endothelial activation is driven by both the local arterial microenvironment, marked by altered extracellular matrix (ECM) composition and disturbed blood flow, and soluble proinflammatory cues such as oxidized low-density lipoprotein (oxLDL). Fibronectin, a provisional extracellular mat...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Cyrine Ben Dhaou, Zaki Al-Yafeai, G. Ali Cruz-Marquez, Matthew L. Scott, Brenna Pearson-Gallion, Elizabeth Cockerham, Hanna Li, Jonette M. Peretik, Yuning Hong, Nirav Dhanesha, Arif Yurdagul, Jr., Oren Rom, Md Shenuarin Bhuiyan, A. Wayne Orr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2025-12-01
Schriftenreihe:Redox Biology
Schlagworte:
ER stress
Inflammation
Oxidized LDL
Shear stress
Integrin
Atherosclerosis
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2213231725004240
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