Cognate antigen engagement on parenchymal cells stimulates CD8+ T cell proliferation in situ

Professional antigen presenting cells (APC) are the major activator of T cells that then hone to sites of inflammation. Using islet cell grafts, here the authors show that parenchymal cells can present antigen to activate CD8+T cells at inflammatory sites, coining this a ‘mezzanine response’ distinc...

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Bibliografiske detaljer

Principais autores:	Robyn M. Sutherland, Sarah L. Londrigan, Jamie L. Brady, Emma M. Carrington, Julia M. Marchingo, Susanne Heinzel, Philip D. Hodgkin, Kate L. Graham, Thomas W. Kay, Yifan Zhan, Andrew M. Lew
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2017-04-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/ncomms14809
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