Sustained yet non-curative response to lenalidomide in relapsed angioimmunoblastic T-cell lymphoma with acquired chidamide resistance: a case report with 10-year follow-up, genetic insights and literature review

Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive subtype of peripheral T-cell lymphoma (PTCL) characterized by its T-follicular helper (TFH) phenotype. Relapsed and refractory disease is common in AITL and often associated with a poor prognosis. The presence of epigenetic abnormalities, im...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Juan Xu, Jie Huang, Liping Xie, Ting Liu, Jianjun Li, Xinchuan Chen, Zhigang Liu, Sha Zhao, Caigang Xu, Yu Wu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-11-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	angioimmunoblastic T-cell lymphoma relapsed lenalidomide chidamide resistance immune dysregulation
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1471090/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!