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Control of replication and gene expression by ADP-ribosylation of DNA in Mycobacterium tuberculosis

Abstract Mycobacterium tuberculosis maintains long-term infections characterised by the need to regulate growth and adapt to contrasting in vivo environments. Here we show that M. tuberculosis complex bacteria utilise reversible ADP-ribosylation of single-stranded DNA as a mechanism to coordinate st...

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Detalhes bibliográficos
Principais autores: Rachel E Butler, Marion Schuller, Ritu Jaiswal, Jayanta Mukhopadhyay, Jim Barber, Suzie Hingley-Wilson, Emily Wasson, Alexassander Couto Alves, Ivan Ahel, Graham R Stewart
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Nature 2025-05-01
Colecção:The EMBO Journal
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Acesso em linha:https://doi.org/10.1038/s44318-025-00451-y
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