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Generation of a LEUTX-2A-mCherry knock-in H1 human embryonic stem cell line using CRISPR/Cas9 system

LEUTX is exclusively expressed at the 8-cell stage and serves as a key regulator of human embryonic genome activation. Induced 8-cell-like cells (8CLCs) derived from pluripotent stem cells offer a tractable model to dissect the molecular transition from pluripotency to totipotency. However, current...

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Váldodahkkit: Xiu Yu, Zezhong Su
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2025-09-01
Ráidu:Stem Cell Research
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S1873506125001047
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