Lymphopenia-induced lymphoproliferation drives activation of naive T cells and expansion of regulatory populations
Summary: Chemotherapy pre-conditioning is an essential component of chimeric antigen receptor transduced cell therapy. Acute lymphopenia-induced proliferation (LIP) is known to be driven primarily by homeostatic cytokines, but little is known on the underlying mechanisms in humans. We undertook phen...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2021-03-01
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| Серии: | iScience |
| Предметы: | |
| Online-ссылка: | http://www.sciencedirect.com/science/article/pii/S2589004221001322 |
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