Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC

Abstract The Legionella pneumophila effector MavC is a transglutaminase that carries out atypical ubiquitination of the host ubiquitin (Ub)‐conjugation enzyme UBE2N by catalyzing the formation of an isopeptide bond between Gln40Ub and Lys92UBE2N, which leads to inhibition of signaling in the NF‐κB p...

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Detalhes bibliográficos

Principais autores:	Hongxin Guan, Jiaqi Fu, Ting Yu, Zhao‐Xi Wang, Ninghai Gan, Yini Huang, Vanja Perčulija, Yu Li, Zhao‐Qing Luo, Songying Ouyang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2020-06-01
coleção:	Advanced Science
Assuntos:	deamidase effectors Legionella pneumophila NF‐κB transglutamination
Acesso em linha:	https://doi.org/10.1002/advs.202000871
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